Mechanisms of Perivascular Adipose Tissue Dysfunction in Obesity

Table 2

Loss of anticontractile effect of PVAT in obesity.

Study reference	Vessel	Type of PVAT	Species	Obesity
[20]	Small arteries (100–150 µm)	Subcutaneous gluteal	Human	Obese patients
[28]	Mesenteric arteries	Mesenteric	C57BL6 mice	DIO (32 w)
[11]	Mesenteric arteries	Mesenteric	NZO mice
[53]	Mesenteric arteries		NZO mice
[19]	Mesenteric arteries	Mesenteric	Rat	DIO (6 mo)
[19]	Aorta	Periaortic	Rat	DIO (6 mo)
[22]	Aorta	Periaortic	Rat	Perinatal nicotine adm
[42]	Coronary	Epicardial	Ossabaw obese swine	DIO (20 w)
[23]	Coronary	Epicardial	Ossabaw obese swine	DIO (6–12 mo)