Protein Glycation in Diabetes as Determined by Mass Spectrometry

Figure 1

MALDI spectra of BSA incubated with 2 M glucose at concentration (pH 7.5; 37°C) recorded at different incubation times: (A) incubation time, 0 days, molecular mass 66429 Da; (B) incubation time, 7 days, molecular mass 71103 Da; (C) incubation time, 14 days, molecular mass 73099 Da; (D) incubation time, 21 days, molecular mass 74279 Da; (E) incubation time, 28 days, molecular mass 74682 Da. From [11], by kind permission of John Wiley and Sons through RightsLink, License no. 3064281057207.