Incidental Thyroid Carcinoma Diagnosed after Total Thyroidectomy for Benign Thyroid Diseases: Incidence and Association with Thyroid Disease Type and Laboratory Markers

Table 3

Biochemical markers (expressed as median values and interquartile range) in relation to the presence of carcinoma, patients’ gender, and preoperative diagnosis.

	TC		𝑃 value
	No	Yes
Total
TgAbs (ng/mL)	20.00 (10.00–41.90)	21.40 (12.25–91.66)	0.657
TPOAbs (U/mL)	12.60 (5.15–29.65)	10.35 (2.00–33.96)	0.329
Tg (ng/mL)	58.00 (20.52–194.00)	62.75 (21.43–421.5)	0.696
Age (years)	50 (40–61)	48 (38–61)	0.785
Females
TgAbs (ng/mL)	21.38 (10.33–85.48)	23.00 (12.50–89.40)	0.695
TPOAbs (U/mL)	13.00 (5.00–36.34)	8.70 (3.25–24.23)	0.274
Tg (ng/mL)	57.75 (24.10–209.82)	60.70 (18.55–204.80)	0.715
Age (years)	50 (40–60)	47 (37–60)	0.623
Males
TgAbs (ng/mL)	14.68 (9.00–29.41)	14.60 (8.40–1224.10)	0.860
TPOAbs (U/mL)	10.98 (5.65–17.15)	17.70 (1.50–102.35)	0.875
Tg (ng/mL)	64.30 (12.40–146.90)	216.80 (25.80–571.02)	0.169
Age (years)	55 (41–63)	60 (37–65)	0.793
Solitary nodule
TgAbs (ng/mL)	21.37 (9.75–33.20)	26.95 (14.60–98.45)	0.364
TPOAbs (U/mL)	11.25 (3.67–21.04)	18.00 (2.00–91.95)	0.352
Tg (ng/mL)	27.00 (12.71–79.17)	45.20 (24.08–503.57)	0.253
Age (years)	42 (28–55)	50 (27–66)	0.422
NTMG
TgAbs (ng/mL)	19.80 (10.00–41.25)	18.20 (10.00–89.40)	0.966
TPOAbs (U/mL)	12.30 (4.18–24.85)	6.25 (2.12–15.98)	0.213
Tg (ng/mL)	56.60 (20.52–142.45)	92.92 (16.75–461.35)	0.380
Age (years)	50 (40–61)	48 (39–61)	0.751

TC: thyroid cancer; NTMG: nontoxic multinodular goiter; 𝑃 value, Mann-Whitney U-test.