Table 1: Quantitative response of all neurons to 10 s stimulation with 20 mM K+. Results are shown as median (5%–95% percentile).

Animal AUC0–180 s %-Δ

Control54930.00 (3.04–110.11)0.92 (0.25–1.47)156.36 (41.77–248.25)
Diabetic57841.41 (3.89–121.72) 1.08 (0.31–1.72) 182.26 (35.86–308.52)

AUC: Area under the curve for 0–180 s, : the absolute change in [Ca2+] (fluorescence ratio), %-Δ: the change in [Ca2+] (fluorescence ratio) measured in % change from baseline.* < 0.001 versus control neurons.