Calcium Activity of Upper Thoracic Dorsal Root Ganglion Neurons in Zucker Diabetic Fatty Rats

Table 2

Quantitative response to 10 s stimulation with 20 mM K⁺. The results were subcategorized according to whether they responded to the capsaicin protocol the respective neuron was stimulated with. Results are shown as median (5%–95% percentile).

Animal	Capsaicin response	𝑛	AUC0–180 s	Δ	%-Δ
Control	Y	157	34.68 (3.05–138.27)	1.05 (0.27–1.65)	175.36 (39.50–290.96)
	N	392	28.02 (3.02–93.19) #	0.88 (0.25–1.30) #	149.64 (42.24–233.10) #
Diabetic	Y	193	42.97 (5.08–155.09)	1.25 (0.38–1.96)∗	202.78 (60.60–353.75)∗
	N	385	40.99 (3.45–105.17) ^*$	1.01 (0.28–1.59) ∗#	170.37 (21.97–288.22) ∗#

AUC: Area under the curve for 0–180 s, Δ: the absolute change in [Ca²⁺]𝑖 (fluorescence ratio), %-Δ: the change in [Ca²⁺]𝑖 (fluorescence ratio) measured in % change from baseline. Y: Yes and N: No. ^∗𝑃 < 0.001 versus corresponding control neurons, ^#P < 0.001 and ^$P < 0.05 versus corresponding capsaicin-responsive neurons.