Research Article

Relationship between Adiponectin Level, Insulin Sensitivity, and Metabolic Syndrome in Type 1 Diabetic Patients

Table 2

Clinical and metabolic characteristics of patients depending on adiponectin concentrations.

VariableAdiponectin < 14.10  g/mLAdiponectin > 14.10  g/mL

Age (years) NS
Gender (m/f)31/716/23NS
Duration of diabetes (years)17.5 (1–41)25 (2–47)0.015
Weight (kg)83 (52–112)68 (54–103)<0.001
BMI (kg/m2) 26 (18–33)24 (20–36)0.027
Waist circumference (cm) <0.002
HbA1c (%) 7.3 (5.41–11.1)7.2 (5.4–12.2)NS
SBP (mmHg) 130 (110–160)125 (100–165)NS
DBP (mmHg)80 (60–110)80 (60–100)NS
eGDR (mg/kg−1 min−1) 6.06 (3.79–10.01)7.67 (3.78–11.65)0.003
LDL cholesterol (mmol/L)2.79 (1.83–5.20)2.74 (1.49–5.32)NS
Total HDL cholesterol (mmol/L)1.46 (0.83–3.83)1.66 (0.78–2.62)NS
HDL2 cholesterol (mmol/L)0.43 (0.20–2.80)0.44 (0.21–1.05)NS
HDL3 cholesterol (mmol/L)1.06 (0.56–1.53)1.23 (0.39–2.28)0.011
Triglycerides (mmol/L) NS
AST (U/L)24 (15–42)22 (13–57)NS
ALT (U/L)27.5 (12–91)22 (12–95)NS
GGT (U/L)25 (13–92)16 (10–59)0.042
ALP (U/L)77 (18–155)75 (36–140)NS
MS presence ( , %)17 (44.7%)9 (23.1%)0.045

ALP: alkaline phosphatase, ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: γ-glutamyltransferase, BMI: body mass index, DBP: diastolic blood pressure, HbA1c: glycated hemoglobin, eGDR: estimated glucose disposal rate, and SPB: systolic blood pressure.