Elevated Serum Gamma-Glutamyltransferase Is a Strong Marker of Insulin Resistance in Obese Children

Table 2

Partial correlation of serum GGT, ALT, and AST with other variables and anthropometric variables in boys.

	GGT	ALT	AST	HOMA-IR
BMI	0.3143*	0.3266*	0.1846*	0.2642*
Waist circumference	0.2395*	0.3230*	0.1851*	0.2749*
BF%	0.1584*	0.1192*	0.1278*	0.0092
Total cholesterol	0.3391*	0.2818*	0.2892*	0.0823
Triglycerides	0.2691*	0.2426*	0.2229*	0.2746*
HDL-cholesterol	−0.1342*	−0.1635*	−0.1222*	−0.0717
Fasting glucose	−0.0393	−0.0817	−0.1289*	0.4464*
Fasting insulin	0.2437*	0.2183*	0.1088*	0.9879*
HOMA-IR	0.2224*	0.1875*	0.0814	—
CRP	0.1362*	0.0950	0.0783	−0.0390
Systolic blood pressure	0.2167*	0.2189*	0.1281*	0.1578*
Diastolic blood pressure	0.2366*	0.1961*	0.1147*	0.0976*
GGT	—	0.7890*	0.6290*	0.2224*

^∗𝑃 value < 0.05 by Spearman’s partial correlation adjusted for age. GGT, ALT, AST, Fasting insulin, HOMA-IR, and CRP were log-transformed.
BMI: body mass index; BF%: body fat percent; CRP: C-reactive protein; HDL: high density lipoprotein; AST: aspartate transaminase; ALT: alanine transaminase; GGT: gamma-glutamyltransferase; HOMA-IR: homeostasis model assessment of insulin resistance.