Research Article

A Network Investigation on Idiopathic Hypogonadotropic Hypogonadism in China

Table 2

Comparison of general characteristics of IHH patients between the present network investigation and studies reported in the literature.

Study groupPresent study single centerNelly Pitteloud* single centerRichard Quinton** multicenter

Study period5 months20 years25 years
Men (%)74 (100)78 (100)170 (79.1)
Age at evaluation (yr) NA
Family history (%)0 (0)19 (24.4)52 (24.2)
Body mass index (kg/m2) NA
Decreased testosterone (%)74 (100)78 (100)170 (100)
Pubertal development (%)5 (6.8)6 (7.7)NA
Small penis (%)16 (21.6)12 (15.4)NA
Testicular volume (mL) 2.1 (1.9–2.3)
Breast enlargement (%)26 (35.1)26 (33.3)NA
Cryptorchidism (%)20 (27.0)23 (29.5)80 (49.7)
Cryptorchidism surgery (%)17 (85.0)67 (85.9)55 (68.8)

Reference [9].
**Reference [10].