Enhanced Healing of Diabetic Wounds by Subcutaneous Administration of Human Umbilical Cord Derived Stem Cells and Their Conditioned Media

Table 3

Analysis of wound closure rate of all groups (mean ± SEM).

Duration; (days)	Area CM; (%)	Area UC-MSC; (%)	Area PBS; (%)
0	0	0	0
2	3.31±0.67	4.13±0.81	2.51±0.09
4	12.01±1.77^∗∗∗	9.10±0.82	3.84±0.32
6	19.98±1.41^∗∗∗	14.75±0.66	6.9±0.60
8	33.72±1.67^∗∗∗	27.63±0.59^∗∗	8.11±0.61
10	61.20±2.12^∗∗∗	59.70±0.41^∗∗	11.64±0.68
12	78.62±1.69^∗	70.71±1.39^∗∗	16.67±0.96
14	94.38±0.80^∗	83.22±1.54^∗∗	18.63±1.13

Note. Comparision of wound closure rates (𝑛=6;^∗𝑃<0.05, CM versus UC-MSC or PBS); (𝑛=6;^∗∗𝑃<0.05, UC-MSC versus PBS); (𝑛=6;^∗∗∗𝑃<0.05, CM versus PBS).