Relationship between Serum Levels of OPG and TGF-β with Decreasing Rate of BMD in Native Chinese Women

Table 1

Demographics and clinical characteristics of the study subjects.

Factor measured	Premenopausal; (𝑛=142)	Perimenopausal; (𝑛=58)	Postmenopausal; (𝑛=265)
Age (years)	40.8 ± 3.50	48.0 ± 2.95	59.7 ± 7.30
Height (cm)	156.2 ± 5.38^b	154.2 ± 5.05^c	151.9 ± 4.54
Weight (kg)	56.9 ± 7.38^c	57.1 ± 8.03^c	54.3 ± 8.46
BMI (kg/m^2)	23.3 ± 2.68	24.0 ± 3.03	23.5 ± 3.34
OPG (pmol/L)^a	2.67 ± 1.86^b	4.11 ± 1.96	4.40 ± 1.85
TGF-β1 (μg/L)^a	39.0 ± 1.60^b	27.1 ± 1.67	24.0 ± 1.52
TGF-β2 (μg/L)^a	11.5 ± 1.28^b	13.0 ± 1.36	14.3 ± 1.32

BMI: body mass index, OPG: osteoprotegerin, and TGF-β: transforming growth factor-beta.
^aValues are geometric mean ± SD.
^b𝑃=0.045–0.000 compared with perimenopausal and postmenopausal.
^c𝑃=0.002–0.000 compared with postmenopausal.