Impaired Growth during Childhood in Patients with Primary Ciliary Dyskinesia
Table 1
Longitudinal data on body length/height and body mass index in a cohort of 29 children with PCD and in a subgroup of 10 children with known biallelic mutations in DNAH5 and DNAI1. The data are expressed as SDS ± SEM; the numbers of subjects with data available are shown in parentheses.
Age (years)
1
3
5
7
9
11
13
15
17
Length/height: all subjects ()
0.40 ± 0.24 ()
0.16 ± 0.23 ()
−0.13 ± 0.21 ()
−0.54 ± 0.19** ()
−0.67 ± 0.21** ()
−0.52 ± 0.24* ()
−0.53 ± 0.23* ()
−0.53 ± 0.29 ()
−0.67 ± 0.38 ()
Length/height: mutation carriers ()
0.17 ± 0.36 ()
0.00 ± 0.41 ()
−0.54 ± 0.38 ()
−0.72 ± 0.31* ()
−0.91 ± 0.30* ()
−0.92 ± 0.46 ()
−0.78 ± 0.46 ()
−0.68 ± 0.60 ()
−0.96 ± 0.56 ()
BMI: all subjects ()
−0.29 ± 0.25 ()
−0.42 ± 0.33 ()
−0.02 ± 0.24 ()
−0.26 ± 0.20 ()
−0.30 ± 0.18 ()
−0.10 ± 0.21 ()
−0.25 ± 0.16 ()
−0.21 ± 0.29 ()
−0.38 ± 0.23 ()
BMI: mutation carriers ()
−0.71 ± 0.54 ()
−0.51 ± 0.93 ()
−0.11 ± 0.60 ()
−0.32 ± 0.33 ()
−0.37 ± 0.31 ()
−0.10 ± 0.26 ()
−0.29 ± 0.22 ()
−0.50 ± 0.32 ()
−0.51 ± 0.34 ()
P < 0.05 and P < 0.01 versus the expected value of 0 SDS.
