Citation
, genderGroup Exercise program Diet restriction Duration of intervention Pre-IL-6 (pg/mL) Post-IL-6 (pg/mL) P valueChanges of body mass (BM), body mass index (BMI), fat mass (FM), and % body fat mass (% BFM) Oberbach et al. [66 ] 9 m, 11 f Normal glucose tolerance Exercise training consisted of 20 min warming and cool-down periods, 20 min of running or biking, and 20 min of powertraining None 4 weeks NS BM, BMI, and %BFM: decrease 9 m, 11 f Impaired glucose tolerance Same as above None 4 weeks NS BM, BMI, and % BFM: decrease 11 m, 9 f T2DM Same as above None 4 weeks NS BM, BMI, and % BFM: decrease Polak et al. [42 ] 25 f Obese premenopausal Aerobic exercise (aerobic exercise performed in gymnasium and cycleergometer) for 45 min on 5 times/week at 50%
O2 max None 12 weeks 3.1 ± 3.7 1.4 ± 1.5 NS BM, BMI, and % BFM: decrease Nassis et al. [68 ] 21 f Overweight/obese girls Aerobic training for 40 min (10 min of warm up, 25 min of physical training games, and 5 minutes of cool down) on 3 times/week None 12 weeks 1.67 ± 1.29 1.65 ± 1.25 NS BM, BMI, and % BFM: NS Bruun et al. [33 ] 11 m, 12 f Obese Exercise training consisted of at least 2-3 h of moderate intensity physical activity (e.g., walking, swimming, aerobics) on 5 times/week Hypocaloric diet calculated to reduce the subject’s body weight by ~1%/week 15 weeks 4.6 ± 0.6 3.4 ± 0.6
BM, BMI, and FM: decrease Kohut et al. [62 ] 40 Overweight aerobic exercise with or without β -blocker treatment Aerobic exercise for 45 min on 3 times/week None 10 months Decrease Significant treatment × time interaction.
BMI: NS 47 Overweight flexibility/strength exercise with or without β -blocker treatment Flexibility/strength exercise for 45 min on 3 times/week None 10 months NS BMI: NS Nicklas et al. [63 ] Base line: 70 6 months: 63: 18 months: 60 Overweight or obese older control None None 18 months 4.7 ± 3.2 Changes 0.19 ± 2.8 (6 months) 0.27 ± 2.8 (18 months) NS BM: NS Base line: 67 6 months: 58: 18 months: 53 Overweight or obese exercise Exercise program consisted of an aerobic phase (15 min), a resistance-training phase (15 min), a second aerobic phase (15 min), and a cool-down phase (15 min) on 3 times/week. None 18 months 4.4 ± 3.1 Changes 0.15 ± 1.8 (6 months) 0.02 ± 2.4 (18 months) NS BM: NS Base line: 71 6 months: 63: 18 months: 53 Overweight or obese dietary WL None Counseling to decrease their energy intake by 500 kcal/day 18 months 4.7 ± 3.4 Changes −0.51 ± 2.1 (6 months) −0.71 ± 2.4 (18 months) Main effect of WL,
BM: decrease Base line: 64 6 months: 58 18 months: 53 Overweight or obese exercise + dietary WL Exercise program consisted of an aerobic phase (15 min), a resistance-training phase (15 min), a second aerobic phase (15 min), and a cool-down phase (15 min) on 3 times/week. Same as above 18 months 4.9 ± 3.0 Changes −0.35 ± 2.15 (6 months) −0.35 ± 1.8 (18 months) Main effect of WL,
BM: decrease