Obesity-Related Metabolic Syndrome: Mechanisms of Sympathetic Overactivity

Figure 1

In obesity, infiltration of inflammatory cells in the white adipose tissue disturbs the secretion of adipokines and increases the activity of adipocyte renin-angiotensin system. Increased secretion of leptin and proinflammatory cytokines and decreased amounts of adiponectin contribute to the development of obesity-related hypertension.