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International Journal of Endocrinology
Volume 2013 (2013), Article ID 895045, 9 pages
http://dx.doi.org/10.1155/2013/895045
Review Article

Novel Adipokines and Bone Metabolism

1Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China
2Geriatric Department, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China
3Neurology Department, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China

Received 15 December 2012; Accepted 2 January 2013

Academic Editor: Guang-Da Xiang

Copyright © 2013 Yuan Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Osteoporosis is a serious social issue nowadays. Both the high morbidity and its common complication osteoporotic fracture load a heavy burden on the whole society. The adipose tissue is the biggest endocrinology organ that has a different function on the bone. The adipocytes are differentiated from the same cell lineage with osteoblast, and they can secrete multiple adipokines with various functions on bone remolding. Recently, several novel adipokines have been identified and investigated thoroughly. In this paper, we would like to highlight the complicated relation between the bone metabolism and the novel adipokines, and it may provide us with a new target for prediction and treatment of osteoporosis.