Clinical Study
Selective Determinants of Low Bone Mineral Mass in Adult Women with Anorexia Nervosa
Table 5
Relationship between bone markers and demographic, nutritional, or hormonal parameters (univariate regression analyses).
| |
Variables | Serum osteocalcin | () | Urinary deoxypyridinoline | () | Regres. coef.
(95% CI) | univar. | | Regres. coef.
(95% CI) | univar. | |
| | Age (yrs) | −0.114 (−0.600; 0.373) | ns | | −0.349 (−0.716; 0.017) | 0.06 | 7% | | Disease duration (yrs) | −0.205 (−0.989; 0.580) | ns | | −0.520 (−1.049; −0.008) | 0.053 | 5% | | Total duration of amenorrhea (months) | 0.024 (−0.077; 0.125) | ns | | 0.000 (−0.078; 0.08) | ns | | | BMI (Kg/m2) | 3.157 (1.416; 4.898) | 0.001 | 24% | −0.450 (−1.561; 0.660) | ns | | | IGF-I (μg/mL): | 0.040 (−0.001; 0.08) | 0.058 | 8% | −0.002 (−0.031; 0.027) | ns | | | IGFBP-3 (mg/mL) | 3.76 (0.630; 6.889) | 0.021 | 24% | 1.0 (−1.319; 3.314) | ns | | | Estrogen use | −2.342 (−10.121; 5.436) | ns | | −4.702 (−9.34; −0.059) | 0.05 | 8% | | Parathyroid hormone (pmol/L) | 0.831 (−3.268; 1.604) | ns | | −1.743 (−3.014; −0. 472) | 0.01 | 14% | | 25-Hydroxyvitamin D (nmol/L) | −0.103 (−0.198; −0.009) | 0.03 | 12% | −0.039 (−0.082; 0.002) | 0.063 | 8% | | Protein intake (g/kg of body weight × d) | −1.996 (−5.116; 1.124) | ns | | 0.027 (−3.080; 3.134) | ns | | | Calcium intake (mg/d) | −0.000 (−0.006; 0.006) | ns | | 0.000 (−0.006; 0.004) | ns | |
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