987186.fig.003
Figure 3: Multiple-sequence alignment of human TPO with those of mouse, rat, pig, dog, chicken, and frog. The alignment data show that valine at position 501 is highly conserved amongst human and many different animal species. The position of the mutated residue (p.Val501Gly) is indicated by the arrow. This figure was generated using the CLC Sequence Viewer 6.5.2 algorithm.