Research Article

High Glucose Aggravates the Detrimental Effects of Pancreatic Stellate Cells on Beta-Cell Function

Figure 6

PSCs-CM induces ER-stress in INS-1 cells in vitro. CHOP mRNA (a) and protein (b) expression were up-regulated in INS-1 cells exposed for 24 h to PSCs-CM or HG alone and, again, their effects were additive.
165612.fig.006a
(a)
165612.fig.006b
(b)