Circulating Sclerostin and Irisin Are Related and Interact with Gender to Influence Adiposity in Adults with Prediabetes
Table 1
Clinical characteristics of the study population according to gender.
Males ()
Females ()
value
Age (years)
61.08 ± 2.49
58.37 ± 1.03
0.32
Body weight (kg)
74.02 ± 2.73
66.24 ± 1.42
0.02
Height (cm)
164.51 ± 1.10
152.42 ± 0.71
<0.001
BMI (kg/m2)
27.25 ± 0.83
28.48 ± 0.60
0.22
WC (cm)
95.21 ± 1.99
96.03 ± 1.37
0.74
FPG (mmol/L)
5.83 ± 0.11
5.80 ± 0.06
0.78
2hPG (mmol/L)
8.75 ± 0.16
8.71 ± 0.17
0.90
HbA1c (%)
6.09 ± 0.06
6.04 ± 0.04
0.53
Irisin (µg/mL)
2.67 ± 0.12
3.08 ± 0.07
<0.01
Sclerostin (pmol/L)
83.38 ± 5.59
70.52 ± 3.49
0.06
Data is expressed as mean ± SEM. BMI: body mass index, WC: waist circumference, FPG: fasting plasma glucose, 2hPG: 2 h plasma glucose, and HbA1c: glycated hemoglobin.
