Taurine Alleviates the Progression of Diabetic Nephropathy in Type 2 Diabetic Rat Model

<table>Differences in VEGF and nephrin mRNA expression in the kidney. (a) Renal VEGF mRNA expression decreased in the taurine-treated diabetic group compared to the diabetic control group. (b) Renal nephrin mRNA expression increased in response to taurine treatment. LETO, normal control group; OLETF, diabetic control group; OLETF + TA, taurine-treated diabetic group. Data are expressed as mean ± SEM. *<svg height="11.375" id="M36" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with LETO; <sup>†</sup><svg height="11.375" id="M37" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><path d="M512 -3l-437 233v51l437 233v-58l-378 -200v-2l378 -199v-58z" id="x3C"></path></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><path d="M241 635q53 0 94 -28.5t63.5 -76t33.5 -102.5t11 -116q0 -58 -11 -112.5t-34 -103.5t-63.5 -78.5t-94.5 -29.5t-95 28t-64.5 75t-34.5 102.5t-11 118.5q0 58 11.5 112.5t34.5 103t64.5 78t95.5 29.5zM238 602q-32 0 -55.5 -25t-35.5 -68t-17.5 -91t-5.5 -105
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</svg> compared with OLETF.</table>

International Journal of Endocrinology

fig4

Figure 4

Figure 4: Taurine Alleviates the Progression of Diabetic Nephropathy in Type 2 Diabetic Rat Model 