MicroRNAs in Human Pituitary Adenomas

Table 1

MicroRNAs and their target genes in human pituitary adenomas.

miRNA	Upregulated or downregulated	Target genes	Tumor type	Reference
let-7	Downregulated	HMGA2	PRL, ACTH FSH/LH	[15]
miR-23b	Downregulated	HMGA2	GH, NFA; FSH/LH	[16]
miR-26a	Upregulated	PRKCD	ACTH	[17]
miR-26b	Upregulated	PTEN	GH	[18]
miR-34b	Downregulated	HMGA1, HMGA2	GH	[19]
miR-107	Upregulated	AIP	GH, NFA	[20]
miR-128	Downregulated	BMI1	GH	[18]
miR-128a	Upregulated	Wee1	NFA	[21]
miR-130b	Downregulated	CCNA2	GH, NFA; FSH/LH	[16]
miR-140-5p	Upregulated	Smad3	NFA	[22]
miR-155	Upregulated	Wee1	NFA	[21]
miR-200c	Upregulated	PTEN	PRL	[23]
miR-326	Downregulated	HMGA2, E2F1	GH	[19]
miR-432	Downregulated	HMGA2	GH	[19]
miR-516a-3p	Upregulated	Wee1	NFA	[21]
miR-548c-3p	Downregulated	HMGA1, HMGA2	GH	[19]
miR-570	Downregulated	HMGA2	GH	[19]
miR-603	Downregulated	E2F1	GH	[19]