Research Article
Behavioural Outcome in Children with Congenital Adrenal Hyperplasia: Experience of a Single Centre
Table 1
Disease characteristics of CAH cases.
| | Male | Female |
| Age (in months) at starting treatmenta | 1.0 (1.5) | 0.5 (0.6) | Age in years at study entry | 11.6 (4.3)a | 11.9 (3.4)a | 11.5 (6–18)b | 12.0 (6–17)b | Presentation at diagnosis | | | Salt wasting featuresc | 17 (85) | 23 (79) | No salt wasting featuresc | 3 (15) | 6 (21) | Ambiguous genitaliac | 0 | 29 (100) | Hypertensionc | 0 | 0 | Height SDS at the time of CBCLa | −1.1 (1.6) | −1.4 (2.2) | Serum 17-OHP in nmol/L at the time of CBCLa | 46.0 (182.1) | 8 (131.1) | Glucocorticoid dose in mg/m2/day near the time of CBCLa | 17.3 (4.9) (CI: 15–19.6) | 14.4 (2.4) (CI: 13.9–15.7) | Prader ratingc | | | 1 | | 4 (14) | 2 | | 8 (28) | 3 | | 14 (48) | 4 | | 3 (10) | Genitoplastyc | | | Nil | | 4 (14) | Clitoroplasty | | 11 (38) | Clitoroplasty and vaginoplasty | | 14 (48) | Age in years at the first genitoplastya | | 2.3 (2.7) | Serum testosterone in nmol/L of CAH girls at the time of CBCLa | | 0.7 (3.3) |
|
|
Mean (standard deviation).
bMedian (range).
cFrequency (%). CI: confidence interval.
|