Serum 25-OH Vitamin D in relation to Bone Mineral Density and Bone Turnover
Table 2
Features, -scores, and biochemical markers of subjects subdivided three times into two groups on the basis of the different 25OHD cutoff values (20, 25, and 30 ng/mL).
Cutoff at 20 ng/mL
Cutoff at 25 ng/mL
Cutoff at 30 ng/mL
25OHD >20 ng/mL ()
25OHD <20 ng/mL ()
25OHD >25 ng/mL ()
25OHD <25 ng/mL ()
25OHD >30 ng/mL ()
25OHD <30 ng/mL ()
Age (years)
57.6 ± 6.4
57.1 ± 6.0
56.6 ± 5.5
57.8 ± 6.2
56.5 ± 6.0
57.7 ± 6.3
BMI (Kg/m2)
26.6 ± 4.4
27.0 ± 3.5
25.9 ± 3.7
27.4 ± 4.1
25.9 ± 3.6
27.2 ± 4.2
Lumbar (L1–L4) -score
−1.9 ± 1.3**
−2.2 ± 1.3
−1.7 ± 1.3**
−2.2 ± 1.6
−1.7 ± 1.3**
−2.1 ± 1.2
Femoral neck -score
−1.2 ± 1.0**
−1.8 ± 1.0
−1.3 ± 1.2**
−1.5 ± 1.0
−1.5 ± 1.0
−1.4 ± 1.0
Osteocalcin (ng/mL)
18.8 ± 12.2
20.5 ± 12.1
18.2 ± 12.3
20.1 ± 11.6
18.2 ± 6.8
20.3 ± 13.5
BAP (μg/mL)
20.2 ± 7.4**
23.1 ± 8.4
19.3 ± 6.6**
23.0 ± 7.1
19.7 ± 6.5*
22.2 ± 9.0
CTX (pmol/L)
4426.2 ± 3546.9*
5439.5 ± 3143.0
4105.3 ± 2162.7*
5324 ± 3395
4002.9 ± 2484.6*
4909.3 ± 3112.0
PTH (pg/mL)
22.2 ± 15.6**
35.5 ± 18.5
20.0 ± 15.8**
33.3 ± 16.4
16.6 ± 13.0**
31.5 ± 19.0
25OHD (ng/mL)
30.2 ± 8.8**
14.4 ± 3.6
33.1 ± 8.6**
16.8 ± 7.8
37.2 ± 8.4**
18.8 ± 5.9
Values are mean ± SD. BMI = body mass index; BAP = bone alkaline phosphatase; CTX = C-telopeptides; PTH = parathormone; 25OHD = 25-hydroxyvitamin D. ** < 0.01 versus subjects with 25OHD values lower than their respective cutoff value. * < 0.05 versus subjects with 25OHD values lower than their respective cutoff value.
