MTNR1B Genetic Variability Is Associated with Gestational Diabetes in Czech Women

Table 3

Subject characteristics based on MTNR1B SNP rs10830963 genotypes.

Group	GDM			Controls
Genotype	CC	CG	GG	CC	CG	GG
BMI (kg/m^2)	24.9 ± 5.05	24.0 ± 4.77	23.8 ± 5.05	23.7 ± 4.16	23.7 ± 4.21	23.3 ± 4.20
Waist circ. (cm)	79.7 ± 10.51	78.1 ± 10.61	78.6 ± 12.31	75.3 ± 10.63	75.2 ± 10.25	74.6 ± 10.98
WHR	0.78 ± 0.06	0.78 ± 0.05	0.78 ± 0.05	0.75 ± 0.07	0.75 ± 0.06	0.75 ± 0.07
Abdominal circ. (cm)	88.3 ± 10.00	86.7 ± 10.79	85.4 ± 10.77	83.0 ± 11.08	82.6 ± 10.95	81.7 ± 10.80
Total body fat (%)	31.7 ± 7.90	30.4 ± 8.28	30.5 ± 7.43	27.4 ± 8.21	28.5 ± 7.59	26.1 ± 7.48
Cholesterol (mmol/L)	4.68 ± 0.821	4.67 ± 0.911	4.43 ± 1.025	4.65 ± 0.92	4.58 ± 0.95	4.68 ± 0.98
HDL (mmol/L)	1.57 ± 0.397	1.63 ± 0.415	1.61 ± 0.317	1.59 ± 0.375	1.60 ± 0.377	1.66 ± 0.331
LDL (mmol/L)	2.69 ± 0.794	2.63 ± 0.879	2.56 ± 0.981	2.65 ± 0.837	2.49 ± 0.840	2.59 ± 1.102
TG (mmol/L)	0.92 ± 0.435	0.92 ± 0.734	0.78 ± 0.419	1.02 ± 0.641	0.99 ± 0.407	1.07 ± 0.589
Testosterone (nmol/L)	1.55 ± 0.61	1.66 ± 0.64	1.59 ± 0.59	1.78 ± 0.753	1.87 ± 0.770	2.05 ± 0.794
DHEA (nmol/L)	16.8 ± 9.93	18.4 ± 10.63	19.7 ± 10.44	19.0 ± 11.24	20.7 ± 13.96	18.3 ± 10.96
DHEAS (umol/L)	4.5 ± 1.97	4.1 ± 1.98	4.31 ± 2.01	4.4 ± 2.50	4.6 ± 2.62	4.1 ± 1.84
Androstenedione (nmol/L)	6.3 ± 2.44	6.4 ± 2.07	6.6 ± 1.87	6.2 ± 2.67	6.4 ± 2.87	6.7 ± 2.57
ALT (ukat/L)	0.32 ± 0.141	0.32 ± 0.169	0.34 ± 0.176	0.30 ± 0.165	0.32 ± 0.177	0.34 ± 0.234
AST (ukat/L)	0.35 ± 0.114	0.37 ± 0.164	0.34 ± 0.09	0.38 ± 0.132	0.39 ± 0.142	0.38 ± 0.141
GGT (ukat/L)	0.30 ± 0.291	0.25 ± 0.269	0.23 ± 0.119	0.26 ± 0.184	0.27 ± 0.202	0.32 ± 0.281
TSH (mIU/L)	3.3 ± 5.69	3.0 ± 4.37	3.3 ± 2.96	2.7 ± 1.44	2.3 ± 1.15	2.9 ± 2.11
fT3 (pmol/L)	5.1 ± 0.76	5.0 ± 0.77	5.1 ± 1.17	4.9 ± 1.17	5.0 ± 1.28	5.2 ± 1.02
fT4 (pmol/L)	15.4 ± 3.85	15.3 ± 2.55	15.2 ± 2.33	15.6 ± 3.13	15.5 ± 4.05	15.4 ± 2.48

Values are given as mean ± SD.