Modified Glomerular Filtration Rate-Estimating Equations Developed in Asiatic Population for Chinese Patients with Type 2 Diabetes
Table 4
Performance between eGFR and sGFR in different subgroups of CKD.
Median of difference (25% and 75% percentile)
Median % absolute difference (25% and 75% percentile)
Accuracy within
CKD stage misclassification
15%
30%
50%
Performance in CKD stages 1-2 ()
Asian equation
20.63 (−1.57, 48.63)*@
35.18 (14.47, 60.13)*
27.4*
43.5*
64.5*
56.5*#
Korean equation
18.91 (−1.67, 30.96)†&
28.58 (10.67, 43.50)
37.1†
51.6*
87.1*#
53.2*&
Japanese equation
−7.25 (−22.04, 9.93)*
20.21 (11.53, 35.64)#
32.3
66.1#
87.1‡
54.8‡#
Thai equation
12.45 (1.06, 53.80)*@
39.16 (16.89, 64.49)*
21.0*
41.9*
59.7*
61.3*#
Chinese equation 1
27.43 (2.89, 63.99)*@
42.13 (18.49, 70.53)*
17.7†
38.7*
56.5*
61.3*#
Chinese equation 2
9.72 (−4.71, 29.98)#
23.48 (9.42, 38.95)
40.3
59.7
85.5
53.2
Simplified reexpressed MDRD equation
13.01 (−6.85, 38.11)*&
27.36 (11.74, 50.44)*
30.6*
53.2*
75.8*
56.5*
CKD-EPI equation
10.06 (−4.94, 26.66)&
19.52 (8.12, 44.31)#
40.3*
64.5*
88.7*&
54.8*#
Performance in CKD stages 3a-3b ()
Asian equation
1.72 (−9.92, 14.04)
27.78 (15.44, 55.86)*
23.5‡
52.9‡
71.8†
74.1‡
Korean equation
10.72 (−3.64, 23.35)*
36.81 (13.90, 53.44)†
25.9
42.4*
69.4
75.3
Japanese equation
−12.02 (−21.52, −2.49)*
32.58 (13.57, 46.99)
29.4
47.1‡
77.6
72.9
Thai equation
3.99 (−8.83, 16.10)‡
29.66 (16.28, 56.38)*
23.5‡
50.6†
69.4†
78.8†
Chinese equation 1
0.98 (−11.56, 14.97)
32.45 (17.48, 58.97)*
20.0†
47.1*
70.6†
76.5†
Chinese equation 2
1.28 (−8.90, 12.10)
24.28 (12.17, 43.60)
34.1
62.4
81.2
65.9
Simplified reexpressed MDRD equation
−2.42 (−12.90, 9.27)*
26.92 (14.145, 6.82)*
27.1
54.1
74.1‡
71.8
CKD-EPI equation
−0.54 (−12.53, 11.77)*
28.72 (14.35, 54.64)*
27.1
55.3
70.6†
71.8
Performance in CKD stages 4-5 ()
Asian equation
−5.87 (−10.49, 1.04)*#
46.04 (25.29, 63.40)*#
12.9
37.1†
59.7*
48.4*&
Korean equation
0.93 (−5.03, 10.03) *#
34.48 (13.27, 65.66)
27.4
43.5*
62.9*
54.8*#
Japanese equation
−8.22 (−12.54, −3.35)*
48.35 (33.95, 65.14)‡@
11.3&
21.0&
53.2&
62.9*
Thai equation
−5.56 (−10.26, 1.62)*#
43.91 (23.56, 62.84)*
8.1‡#
37.1*
61.4*
51.6*@
Chinese equation 1
−6.41 (−11.55, −0.47)*#
49.28 (27.83, 66.21)†
14.5
27.4#
51.6†#
51.6*&
Chinese equation 2
−1.95 (−6.94, 5.16)
29.43 (14.67, 52.26)
25.8
51.6
72.6
41.9&
Simplified reexpressed MDRD equation
−6.48 (−11.30, −0.21)*
46.90 (30.80, 64.90)‡&
12.9&
22.6@
51.6†&
53.2*#
CKD-EPI equation
−6.90 (−11.56, −0.47)*
50.08 (32.79, 66.25)†&
12.9#
22.6@
48.4†&
54.8*#
eGFR: estimated glomerular filtration rate; sGFR: standard glomerular filtration rate; CKD: chronic kidney disease.
*
compared with Chinese equation 2-GFR. † compared with Chinese equation 2-GFR. ‡ compared with Chinese equation 2-GFR.
@ compared with the subgroup with CKD stages 3a-3b.
& compared with the subgroup with CKD stages 3a-3b.
# compared with the subgroup with CKD stages 3a-3b.
