Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis

Table 2

The expression of the genes studied in patients with Hashimoto’s thyroiditis and healthy controls.

Gene	Control group 𝑛=15	Hashimoto’s thyroiditis 𝑛=39	𝑃 value
NIS (AU)	0.22 (0.04–0.75)	0.12 (0.003–0.60)	0.001
Thyroglobulin (AU)	56.60 (21.34–87.96)	25.60 (1.38–20.16)	0.002
TNF-𝛼 (AU)	0.015 (0.002–0.03)	0.029 (0.016–0.03)	0.049
IL-1𝛽 (AU)	0.002 (0.0006–0.009)	0.015 (0.002–0.018)	0.26

Data are shown as medians (interquartile range); differences between groups were tested by Mann-Whitney 𝑈 test; AU: arbitrary units.