Prevalence of Nonclassic Congenital Adrenal Hyperplasia in Turkish Children Presenting with Premature Pubarche, Hirsutism, or Oligomenorrhoea

Table 1

Clinical characteristics and laboratory findings of study subjects.

	Subjects without NCAH	Subjects with NCAH	𝑃 value
Age (year)	8,80 (7,30–14,60)	7,80 (6,80–13,30)	0,336
Gender (female/male)	113/4	9/0	0,741
BMI SDS	0,82±0,09	1,03±0,36	0,572
Height SDS	0,33±1,10	0,49±0,39	0,685
Bone Age SDS	1,02±0,09	2,07±0,12	0,002
Ferriman Gallway Score	20,18±4,65	23,00±5,00	0,594
T.Testosterone (ng/dL)	16,50 (0,69–38,37)	7,05 (0,79–20)	0,752
Cortisol0 (𝜇g/dL)	14,41±5,72	13,75±5,68	0,740
Cortisol1 hour (𝜇g/dL)	28,69±5,66	32,47±5,30	0,055
17-OHP0 (ng/mL)	1,20 (0,90–2)	3,90 (2,15–9,50)	<0,001
17-OHP1 hour (ng/mL)	3,10 (2,25–4,40)	21,60 (9,80–34,05)	<0,001
DHEA-S0 (𝜇g/dL)	103 (53,50–181,50)	128 (128–331,50)	0,619
DHEA-S1 hour (µg/dL)	102 (53,70–188,50)	130 (50,50–312,50)	0,622

Data are expressed as the means ± standard deviations or medians (Q1–Q3) as appropriate. NCAH: nonclassic congenital adrenal hyperplasia; BMI-SDS: body mass index standard deviation score; 17-OHP: 17-hydroxyprogesterone; DHEA-S: dehydroepiandrosterone sulphate.