Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia

Table 3

Preoperative clinical manifestations in the two groups of patients.

Symptom	CD ( = 48)	PRL + CD ( = 36)	P
Headache/dizziness	27 (56.3%)	24 (66.7%)	0.333
Progressive obesity	21 (43.8%)	6 (16.7%)	0.009
Vomiting	4 (8.3%)	4 (11.1%)	0.720
Visual impairment	19 (39.6%)	18 (50.0%)	0.341
Visual field defects	6 (12.5%)	12 (33.3%)	0.021
Menstrual disorders	16/28 (57.1%)	22/26 (84.6%)	0.027
Galactorrhea	10/28 (35.7%)	14/26 (53.8%)	0.180
Sexual dysfunction	4/10 (40.0%)	2/20 (10.0%)	0.141
Polyuria/polydipsia	12 (25.0%)	8 (22.2%)	0.767
Hypertension	40 (83.3%)	10 (27.8%)	<0.001
Diabetes mellitus	5 (10.4%)	6 (16.7%)	0.523

Data are expressed as (%). values were determined using a chi-square test. P < 0.05 was considered statistically significant.