Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia

Table 4

The levels of cortisol (nmol/L) and PRL (ng/mL) measured during follow-up of the patients in the two groups.

Group	Hormone	Before surgery	3 days after surgery	3 months after surgery	12 months after surgery
CD; ( = 48)	Cortisol	833.87 ± 235.75^*	336.87 ± 267.56	320.64 ± 213.54	332.01 ± 229.81	54.098	<0.001
	PRL	13.77 ± 6.87^△	11.12 ± 6.71^△	12.93 ± 6.57^△	12.66 ± 6.20^△	1.345	0.305
PRL + CD; ( = 36)	Cortisol	673.24 ± 65.53	375.83 ± 187.51	385.24 ± 186.57	368.33 ± 170.87	30.713	<0.001
	PRL	233.63 ± 188.06	72.63 ± 66.94	74.51 ± 62.58	77.43 ± 70.38	18.64	<0.001

Data are expressed as the mean ± SD. * indicates a significant difference in the cortisol level between the two groups at the same time point (P < 0.05). △ indicates a significant difference in the PRL level between the two groups at the same time point (P < 0.05). Each P value shown in the Table is for comparative analysis, within the CD or PRL + CD group, between values before surgery and those 3 days after surgery.