High Prevalence of Infertility among Women with Graves’ Disease and Hashimoto’s Thyroiditis

Table 3

Comparative analysis of the mean number of pregnancies prior to and following diagnosis of GD and HT in accordance with the woman’s age at diagnosis.

Number of pregnancies^a	Woman’s age				All women
	≤35 years	𝑃 value	>35 years	𝑃 value	All age	𝑃 value
Graves’ disease	(𝑛=84)		(𝑛=109)		(𝑛=193)
Prior to diagnosis*	1.68 (1.41)	<0.001	3.07 (1.64)	<0.001	2.47 (1.69)	<0.001
Following diagnosis^#	0.67 (0.96)		0.07 (0.3)		0.33 (0.73)
Hashimoto’s thyroiditis	(𝑛=27)		(𝑛=39)		(𝑛=66)
Prior to diagnosis*	1.48 (1.31)	0.02	3.23 (2.01)	<0.001	2.52 (1.95)	<0.001
Following diagnosis^#	0.67 (0.62)		0.03 (0.16)		0.29 (0.52)

aAll values are means ± SD. Wilcoxon test. Mann Whitney test for comparison between the two age subgroups: GD^∗(𝑃 value < 0.001), ^#(𝑃 value < 0.001); HT^∗(𝑃 value < 0.001), ^#(𝑃 value < 0.001).