Research Article
Treated Autoimmune Thyroid Disease Is Associated with a Decreased Quality of Life among Young Persons with Type 1 Diabetes
Table 2
Quality of life assessed using the HRQOL questionnaires, by thyroid disease.
| | |
All patients | Thyroid disease status | -test value | | | No thyroid disease | T1D + AB | T1D + AITD | T1D + AB
versus no thyroid disease | T1D + AITD
versus no thyroid disease |
| | Children’s scores | | Generic HRQOL questionnaire | | | | | | | | Overall | 82.51 (10.81) | 83.57 (10.47) | 82.64 (10.93) | 78.55 (11.17) | 0.567 | | | Physical functioning | 87.93 (10.58) | 88.47 (10.35) | 88.91 (10.21) | 84.45 (11.48) | 0.777 | 0.051 | | Emotional functioning | 74.43 (18.57) | 76.67 (18.21) | 72.75 (18.59) | 69.20 (18.95) | 0.161 | | | Social functioning | 90.92 (12.53) | 91.25 (11.19) | 92.03 (13.24) | 88.00 (15.43) | 0.682 | 0.220 | | School functioning | 73.77 (16.12) | 75.39 (15.64) | 73.28 (16.79) | 68.88 (16.03) | 0.396 | | | Diabetes-specific HRQOL questionnaire | | | | | | | | Overall | 76.90 (12.24) | 78.46 (12.25) | 75.86 (12.15) | 73.05 (11.56) | 0.158 | | | Diabetes symptoms | 73.29 (13.71) | 74.76 (14.00) | 72.77 (12.83) | 68.87 (13.41) | 0.318 | | | Treatment barriers | 77.60 (17.07) | 78.71 (17.64) | 75.85 (16.57) | 76.49 (15.86) | 0.261 | 0.452 | | Treatment adherence | 84.82 (13.45) | 86.96 (12.10) | 83.15 (15.38) | 79.92 (13.34) | 0.082 | | | Worry | 73.77 (21.92) | 75.03 (22.14) | 73.65 (21.81) | 69.35 (21.28) | 0.681 | 0.159 | | Communication | 81.07 (19.79) | 82.66 (18.70) | 79.83 (20.42) | 77.39 (22.30) | 0.352 | 0.189 |
| | Parental scores | | Generic HRQOL questionnaire | | | | | | | | Overall | 78.47 (11.20) | 79.57 (11.19) | 77.97 (11.22) | 75.30 (10.85) | 0.350 | 0.039 | | Physical functioning | 83.55 (11.79) | 84.53 (11.37) | 83.40 (12.84) | 80.24 (11.11) | 0.551 | 0.043 | | Emotional functioning | 71.38 (17.07) | 72.94 (17.60) | 69.37 (16.18) | 69.19 (16.39) | 0.162 | 0.230 | | Social functioning | 86.86 (14.22) | 87.15 (13.63) | 88.38 (13.70) | 83.24 (16.76) | 0.557 | 0.198 | | School functioning | 69.14 (16.56) | 70.74 (16.52) | 67.78 (17.96) | 65.68 (13.70) | 0.193 | 0.061 | | Diabetes-specific HRQOL questionnaire | | | | | | | | Overall | 74.13 (12.43) | 75.09 (12.95) | 72.91 (12.27) | 72.70 (10.64) | 0.251 | 0.253 | | Diabetes symptoms | 71.70 (13.15) | 73.20 (13.53) | 69.94 (13.04) | 69.19 (11.37) | 0.105 | 0.072 | | Treatment barriers | 74.48 (17.62) | 75.04 (18.12) | 73.69 (17.42) | 73.81 (16.44) | 0.615 | 0.695 | | Treatment adherence | 79.62 (16.11) | 81.02 (15.22) | 77.31 (18.70) | 78.46 (14.27) | 0.167 | 0.343 | | Worry | 72.12 (22.13) | 72.43 (22.72) | 72.36 (22.84) | 70.53 (23.92) | 0.985 | 0.630 | | Communication | 76.25 (23.19) | 75.91 (23.32) | 76.16 (22.84) | 77.67 (23.92) | 0.944 | 0.695 |
|
|
Data are mean (SD).
Test for trend across the categories “no thyroid disease” > “T1D + AB” > “T1D + AITD” significant at < 0.05 and < 0.005.
|
