Effect of Omega-3 Fatty Acid on the Fatty Acid Content of the Erythrocyte Membrane and Proteinuria in Patients with Diabetic Nephropathy
Table 2
Comparison of erythrocyte membrane fatty acids content.
Control ( = 32)
DM ( = 19)
value1
Saturated
39.0 ± 6.1
42.7 ± 7.3
0.081
Myristic
0.57 ± 0.29
0.72 ± 0.32
0.065
Palmitic
24.4 ± 4.0
26.6 ± 4.8
0.159
Stearic
13.9 ± 2.9
15.1 ± 3.5
0.097
Lignoceric
0.23 ± 0.12
0.27 ± 0.17
0.614
Monounsaturated
16.2 ± 2.6
17.6 ± 2.9
0.085
Palmitoleic
1.8 ± 1.7
1.2 ± 0.8
0.437
Trans-oleic
1.7 ± 0.7
1.2 ± 0.9
0.036*
Oleic
13.9 ± 2.4
15.9 ± 3.0
0.020*
Polyunsaturated
42.0 ± 7.6
37.4 ± 8.3
0.038*
Omega-6
28.9 ± 5.7
27.2 ± 5.7
0.166
Linoleic
13.5 ± 3.0
14.4 ± 4.4
0.785
AA
11.7 ± 3.1
9.4 ± 3.0
0.014*
Omega-3
13.1 ± 3.4
10.2 ± 3.9
0.011*
Alpha-linolenic
0.35 ± 0.19
0.49 ± 0.21
0.026*
EPA
2.0 ± 0.9
1.9 ± 1.1
0.556
DHA
8.3 ± 2.3
6.0 ± 2.2
0.002*
Omega-3 index
10.3 ± 2.9
7.9 ± 3.1
0.008*
AA/EPA
7.3 ± 4.4
7.1 ± 6.0
0.644
Omega-6/Omega-3
2.3 ± 0.7
3.0 ± 1.1
0.025*
Data are expressed as means ± SD. value for nonparametric Mann-Whitney test comparing baseline data between control group and DM group. value <0.05 (mean values are significantly different from control group). AA: arachidonic acid; EPA: eicosapentaenoic acid; DHA: docosahexaenoic acid; DM: diabetes mellitus.
