The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes

Table 2

The triglycerides, total cholesterol, LDL and HDL cholesterol levels, and ratio of LDL/HDL cholesterol in diabetic and control rats on the 150th day of experiment and the influence of the treatment with IS.

	Triglycerides, mM	Total cholesterol, mM	HDL cholesterol, mM	LDL cholesterol, mM	LDL cholesterol/HDL cholesterol ratio
C0 ()	0.85 ± 0.13	4.49 ± 0.35	2.89 ± 0.14	1.42 ± 0.17	0.49 ± 0.04
ND + SER ()	1.12 ± 0.16^#	5.02 ± 0.30^#	2.61 ± 0.18^#	1.74 ± 0.16^#	0.67 ± 0.04^##
D0 ()	1.63 ± 0.28	6.42 ± 1.08	2.86 ± 0.16	2.96 ± 0.63	1.03 ± 0.20
D + SER ()	1.35 ± 0.14^#	5.65 ± 0.56	3.03 ± 0.23	2.33 ± 0.34^#	0.77 ± 0.11^#

Note. The data are presented as M ± SD. () The difference between Groups C0 and D0 and () the difference between Groups C0 and ND + SER or between Groups D0 and D + SER are significant at and , respectively.