Efficacy of Subantimicrobial Dose Doxycycline for Moderate-to-Severe and Active Graves’ Orbitopathy

Figure 1

Representative example of patients status at baseline and at 24 wk after the start of treatment. (a) (baseline) and (b) (24 wk) showed that soft tissue involvements and redness of conjunctiva were remarkably improved in a female at 24 wk. (c) (baseline) and (d) (24 wk) showed the improvement of eyelid aperture, lid lag, and elevation in a male treated by doxycycline.

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