Simultaneous Quantification of 25-Hydroxyvitamin D<sub>3</sub> and 24,25-Dihydroxyvitamin D<sub>3</sub> in Rats Shows Strong Correlations between Serum and Brain Tissue Levels

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">Analytes</td><td align="center">MRM transition</td><td align="center">CE</td><td align="center">Dwell</td></tr><tr class="thead"><td align="center">(<svg height="6.20645pt" id="M1" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -6.00005 10.6039 6.20645" width="10.6039pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M781 91L765 118C733 86 702 70 693 70C686 70 685 77 692 106L738 297C772 439 736 451 712 451S675 445 647 431C605 410 526 356 452 257H450L459 294C491 426 459 451 429 451C403 451 386 445 361 431C312 404 239 343 170 253H168L188 333C208 411 205 451 175 451C148 451 85 417 24 346L39 318C57 338 100 374 112 374C120 374 122 372 115 339C91 226 62 112 28 -6L37 -12C59 -4 87 3 114 6C125 68 142 127 154 168C184 227 316 383 372 383C397 383 396 366 381 289C362 192 338 92 312 -6L317 -12C339 -5 367 3 396 6L434 170C468 234 598 383 650 383C668 383 676 369 664 319L609 90C593 23 600 -12 629 -12C654 -12 722 23 781 91Z" id="g50-110"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="805" vert-adv-y="805"></glyph.data></g></svg>/<svg height="6.54572pt" id="M2" style="vertical-align:-0.3368902pt" version="1.1" viewbox="-0.0498162 -6.20883 6.68923 6.54572" width="6.68923pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M481 445L456 468C426 437 403 427 388 427C372 427 356 428 302 438C256 447 221 451 187 451C159 451 130 428 105 384C93 363 80 340 65 305L96 290C122 342 149 381 193 381C216 381 267 377 294 374S346 372 365 376L75 105C37 70 24 35 24 16C24 2 30 -5 35 -8C42 -8 46 -6 48 -2C58 14 75 35 90 41C102 46 116 46 147 32C200 8 267 -21 298 -21C347 -21 390 12 448 126L420 151C369 77 338 56 311 56C287 56 249 68 212 81C180 92 149 100 127 98C212 172 353 308 413 372L481 445Z" id="g50-123"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="505" vert-adv-y="505"></glyph.data></g></svg>)</td><td align="center">(V)</td><td align="center">(ms)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">25(OH)D<sub>3</sub>-PTAD</td><td align="center">558/298</td><td align="center">25</td><td align="center">100</td></tr><tr><td align="left">24,25(OH)<sub>2</sub>D<sub>3</sub>-PTAD</td><td align="center">574/298</td><td align="center">30</td><td align="center">100</td></tr><tr><td align="left">d6-25(OH)D<sub>3</sub>-PTAD</td><td align="center">564/298</td><td align="center">25</td><td align="center">100</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

International Journal of Endocrinology

tab1

Table 1

Table 1: Simultaneous Quantification of 25-Hydroxyvitamin D<sub>3</sub> and 24,25-Dihydroxyvitamin D<sub>3</sub> in Rats Shows Strong Correlations between Serum and Brain Tissue Levels 

Table 1 | Simultaneous Quantification of 25-Hydroxyvitamin D3 and 24,25-Dihydroxyvitamin D3 in Rats Shows Strong Correlations between Serum and Brain Tissue Levels 