Increased Serum Pigment Epithelium-Derived Factor in Women with Gestational Diabetes Is Associated with Type 2 Diabetes
Table 1
Clinical and biochemical characteristics of gestational diabetes mellitus (GDM) patients and controls.
Parameter
GDM ()
Control ()
P value
Age (years)
30.14 ± 3.35
29.87 ± 3.07
0.421
Week of gestation
27.4 ± 1.5
26.8 ± 1.2
0.581
Weight (kg)
56.71 ± 5.48
55.98 ± 5.21
0.204
Height (cm)
158.42 ± 4.51
158.01 ± 4.27
0.618
Prepregnancy BMI (kg/m2)
23.49 ± 3.47
22.31 ± 2.71
0.178
Total cholesterol (mg/dl)
175.01 ± 21.31
183.14 ± 23.14
0.214
Triglyceride (mg/dl)
91.23 ± 51.31
84.12 ± 43.56
0.276
HDL-C (mg/dl)
47.19 ± 10.3
68.12 ± 9.6
0.105
LDL-C (mg/dl)
107.13 ± 20.18
97.18 ± 19.25
0.205
Glucose 0 h (mmol/L)
4.92 ± 0.91
4.21 ± 0.42
0.032
Glucose 1 h (mmol/L)
10.7 ± 1.72
7.12 ± 1.32
<0.01
Glucose 2 h (mmol/L)
9.02 ± 1.03
6.14 ± 1.26
<0.01
Fasting insulin (pmol/l)
68.13 ± 12.12
55.35 ± 7.12
0.037
HOMA-IR
2.67 ± 1.23
1.62 ± 0.67
<0.01
Adiponectin (mg/l)
12.34 ± 6.12
23.05 ± 7.12
<0.01
PEDF (μg/ml)
5.02 ± 2.12
3.34 ± 1.23
<0.01
The difference of values between GDM patients and controls was performed by independent-samples -test; was considered to be significantly different; BMI: body mass index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; PEDF: pigment epithelium-derived factor.
