Clinical Study
Cushing’s Disease: The Relevance of a Combined Dexamethasone Desmopressin Test as a Component of Postoperative Hormonal Evaluation
Table 3
Absolute (Δ) changes in cortisol and ACTH levels at consecutive time points compared to baseline, stratified by remission status.
| | Remission () | Persistent CD () | value | | Mean ± SD | Median | Range | Mean ± SD | Median | Range |
| Cortisol (μg/dL) | | | | | | | | 15′ | 0.81 ± 2.86 | 0.0 | −0.1–11.1 | 8.71 ± 6.20 | 9.8 | 0.2–20.3 | <0.001 | 30′ | 0.89 ± 3.06 | 0.1 | −0.2–11.9 | 12.90 ± 7.10 | 13.8 | 0.3–22.3 | <0.001 | 60′ | 0.60 ± 2.01 | 0.0 | −0.2–7.8 | 14.50 ± 7.80 | 14.0 | 0.3–24.8 | <0.001 | 90′ | 0.41 ± 1.32 | 0.0 | −0.2–5.1 | 13.14 ± 8.55 | 13.7 | −0.1–28.7 | <0.001 | 120′ | 0.28 ± 1.07 | 0.0 | −0.1–4.1 | 10.97 ± 8.77 | 9.2 | −0.8–32.6 | <0.001 | ACTH (pg/mL) | | | | | | | | 15′ | 5.02 ± 7.17 | 2.0 | 0.0–27.0 | 151.31 ± 292.89 | 55.0 | 1.0–1093.0 | <0.001 | 30′ | 3.19 ± 4.42 | 1.0 | −0.5–16.0 | 128.15 ± 227.38 | 56.0 | 3.0–858.0 | <0.001 | 60′ | 1.16 ± 2.08 | 0.5 | −1.0–5.0 | 66.85 ± 120.70 | 33.0 | 1.0–460.0 | <0.001 | 90′ | 0.23 ± 1.41 | 0.0 | −2.0–4.0 | 50.69 ± 106.12 | 25.0 | 2.0–399.0 | <0.001 | 120′ | −0.25 ± 1.51 | 0.0 | −3.0–3.0 | 38.39 ± 96.01 | 9.0 | −2.0–353.0 | 0.002 |
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