Research Article

Association Analysis of MET Gene Polymorphism with Papillary Thyroid Carcinoma in a Chinese Population

Table 1

Allele and genotype frequency of MET SNPs in patients with PTC and NG and NC.

METPTC ()NG ()NC () value

rs1621
 AA657 (76.6%)449 (80.8%)724 (80.8%)0.050
 AG193 (22.5%)98 (17.6%)158 (17.6%)
 GG8 (0.9%)9 (1.6%)14 (1.6%)
 A1507 (87.8%)996 (89.6%)1606 (89.6%)0.176
 G209 (12.2%)116 (10.4%)186 (10.4%)
rs6566
 AA178 (20.7%)131 (23.7%)214 (24.1%)0.161
 AG433 (50.3%)273 (49.4%)458 (51.6%)
 GG250 (29%)149 (26.9%)216 (24.3%)
 A789 (45.8%)535 (48.4%)886 (49.9%)0.053
 G933 (54.2%)571 (51.6%)890 (50.1%)

PTC: papillary thyroid cancer; NG: nodular goiter; NC: normal control.