The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis

Table 3

Comparison of clinicopathologic characteristics between WLPTC and classic PTC coexisting with HT.

Characteristic	Classic PTC with HT ()	WLPTC ()	value
Mean age (years)	46 (25–73)	46 (18–77)	0.892
Age			0.833
<45	21 (40%)	17 (43%)
≥45	32 (60%)	23 (58%)
Sex			0.081
Female	52 (98%)	35 (88%)
Male	1 (2%)	5 (13%)
Multifocality			0.207
Unifocal	25 (47%)	25 (63%)
Multifocal	28 (53%)	15 (38%)
Surgery type			0.611
Lobectomy	12 (23%)	7 (18%)
Total thyroidectomy	41 (77%)	33 (83%)
Median tumor size (cm)	0.7 (0.3–4.5)	1.0 (0.4–2.2)	0.285
pT stage			0.467
pT1	34 (64%)	30 (75%)
pT2	1 (2%)	1 (3%)
pT3	18 (34%)	9 (23%)
Extrathyroidal extension			0.257
Absent	35 (66%)	31 (78%)
Present	18 (34%)	9 (23%)
pN stage			0.833
pN0	31 (59%)	22 (55%)
pN1	22 (42%)	18 (45%)
Preoperative diagnosis			0.675
Atypia of undetermined significance	2 (4%)	2 (5%)
Suspicious for PTC	13 (25%)	7 (18%)
PTC	38 (72%)	31 (78%)
BRAF mutation			0.494
Absent	14 (26%)	14 (35%)
Present	39 (74%)	26 (65%)

PTC, papillary thyroid carcinoma; WLPTC, Warthin-like variant of papillary thyroid carcinoma; HT, Hashimoto’s thyroiditis.