The Association of Metabolic Syndrome and Urolithiasis

Table 3

ABCDE approach to managing metabolic syndrome [52].

A	Aspirin		All patients with > 6% 10 year risk (without contraindications)
B	Blood pressure control	Goal	<130/80 mmHg if at intermediate risk (>6% 10 year risk)
		First line	ACEI or ACE
		Alternatives	-blocker or diuretics may increase risk of diabetes
C	Cholesterol management
	LDL-C	Goal	<130 mg/dL if at intermediate risk; <100 mg/dL if at high risk
		First line	Statins
	Non-HDL-C	Goal	<160 mg/dL if at intermediate risk; <130 mg/dL if at high risk
		First line	Statins, fenofibrate
		Alternatives	Omega-3 fatty acid supplement
	HDL-C		Long acting niacin may increase risk of glucose intolerance
D	Diabetes prevention	First line	Lifestyle modification
		Second line	Metformin, pioglitazone
	Diet		Weight loss, low glycemic load
E	Exercise		Daily moderate to rigorous exercise; Recommend use of pedometer with goal of >10000 steps/day