Cardiovascular System Changes and Related Risk Factors in Acromegaly Patients: A Case-Control Study

Table 3

Relationship between echocardiography and potential risk factors.

	HCE+ ()	HCE− ()		MCH+ ()	MCH− ()		GVE+ ()	GVE− ()		DFD+ ()	DFD− ()
Male,	16	28	0.10	6	38	0.37	4	40	0.86	7	37	0.34
Age, years						<0.001			0.24			<0.001
BMI, kg/m^2						<0.001			0.30			<0.001
Smoking,	17	29	0.07	10	36	0.33	4	42	0.95	12	34	0.20
HT,	10	20	0.42	8	22	0.13	5	25	0.06	10	20	0.04
DM,	15	44	0.55	15	44	0.02	5	54	0.92	17	42	0.02
Dyslipidemia,	6	9	0.41	6	9	0.04	0	15	0.52	7	8	0.02
Nadir GH, ng/mL			0.31			0.23			0.49			0.003
Fasting GH, ng/mL			0.54			0.33			0.41			0.001
IGF-1, ng/mL			0.91			>0.99			0.23			0.45
DD, month			0.09			0.04			<0.001			0.002

HCE = heart chamber expansion; MCH = myocardial hypertrophy; DFD = diastolic function decline; GVE = great vessel expansion; HT = hypertension; DM = diabetes mellitus; BMI = body mass index; DD = disease duration; and IGF-1 = insulin-like growth factor.