Treatment of Primary Aldosteronism and Organ Protection

Table 2

Summary of results obtained in studies that evaluated the long-term response of left ventricular mass to either medical treatment or surgical treatment in primary aldosteronism.

Study	Follow-up years	Medical treatment		Surgical treatment
		Baseline	End of study	Baseline	End of study
Catena et al.,; 2007 [28]	6.4	52 ± 2	44 ± 2^†	53 ± 2	43 ± 2
Giacchetti et al.; 2007 [49]	3.7	135 ± 4	125 ± 7	126 ± 5	116 ± 5
Bernini et al.,; 2012 [50]	2.7	65 ± 2	65 ± 3	58 ± 2	49 ± 3
Rossi et al.,; 2013 [48]	3.0	50 ± 1	47 ± 1	53 ± 1	49 ± 1

Values of left ventricular mass index are expressed as g/m^2.7 except for the study of Giacchetti et al. () that expressed as left ventricular mass (g). ^† versus baseline.
Data in the table have been included in a meta-analysis [51] showing that effects of medical and surgical treatment of primary aldosteronism on left ventricular mass are not significantly different.