High Serum IgG4 Concentrations in Patients with Hashimoto’s Thyroiditis
Table 1
Ultrasonographic and biochemical characteristics of the patients with non-IgG4-HT, IgG4-HT, and the control group.
Non-IgG4-HT IgG4 < 135 IU/mL = 40
IgG4-HT IgG4 > 135 IU/mL = 13
Control group = 28
Thyroid volume (mL)
12.1 (7.9–14.9)
13.0 (10.1–17.2)
ns
18.5 (12.5–19.5)
0.001
Thyroid nodules ()
1.0 (1.0–2.0)
2.0 (1.0–2.0)
0.02
—
TSH (IU/mL)
1.5 (0.98–1.9)
1.2 (0.95–2.1)
ns
1.1 (0.9–1.4)
TPOAb (IU/L)
248.3 (40.4–413.3)
11.0 (4.6–294.9)
0.02
6.1 (4.9–10.2)
0.00001
TRAb (IU/L)
1.1 (0.8–1.3)
1.3 (0.8–1.7)
ns
0.3 (0.3–0.5)
0.00001
Levothyroxine dose (ug/day)
50.0 (0–81.3)
75.0 (50.0–88.0)
ns
Data are shown as medians (interquartile range); differences between groups were tested by Mann-Whitney test. : between IgG4-HT and non-IgG4-HT; : between IgG4-HT and control group.
