High Serum IgG4 Concentrations in Patients with Hashimoto’s Thyroiditis
Table 3
Proinflammatory cytokines and apoptotic markers in the patients with non-IgG4-HT, IgG4-HT, and the control group.
Non-IgG4-HT IgG4 < 135 IU/mL = 40
IgG4-HT IgG4 > 135 IU/mL = 13
Control group = 28
IgG4 (IU/mL)
60.1 (25.3–75.9)
163.6 (131.5–208.7)
0.001
96.3 (42.7–112.2)
ns
TGF-1 (pg/mL)
30361 (26019–32897)
33732 (29897–36800)
0.05
32293 (29017–38791)
ns
TNF-α (pg/mL)
5.7 (5.0–7.2)
6.1 (5.6–8.2)
ns
5.3 (4.1–6.4)
0.01
TRAIL (pg/mL)
109.2 (93.2–133.7)
110.3 (83.8–113.3)
ns
107.2 (87.3–129.6)
ns
Fas Ligand (pg/mL)
90.3 (76.6–104.9)
82.5 (74.2–130.2)
ns
87.7 (68.4–111.7)
ns
CXCL9 (pg/mL)
70.6 (52.7–95.7)
88.7 (69.1–116.4)
ns
62.7 (51.3–92.5)
ns
CXCL10 (pg/mL)
94.7 (79.9–120.7)
95.3 (77.4–130.2)
ns
96.0 (96.3–129.6)
ns
CXXL11 (pg/mL)
59.8 (24.7–77.2)
52.5 (24.7–63.4)
ns
56.2 (37.2–110.0)
ns
Data are shown as medians (interquartile range); differences between groups were tested by Mann-Whitney test. : between IgG4-HT and non-IgG4-HT; : between IgG4-HT and control group.
