Thyroid Function, Prevalent Coronary Heart Disease, and Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

Table 1

Characteristics of the study population by coronary heart disease and noncoronary heart disease.

Variables	Coronary heart disease	Noncoronary heart disease	value
	( = 1490)	( = 309)
Male (%)	78.52	60.52	<0.001
Age (years)	62.93 ± 0.26	61.46 ± 0.58	0.02
BMI (Kg/m^2)	24.79 ± 0.08	24.73 ± 0.19	0.77
Diabetes (%)	36.44	24.92	<0.001
FPG (mmol/L)	5.76 ± 0.04	5.44 ± 0.07	<0.001
2-h PPG (mmol/L)	9.40 ± 0.11	8.34 ± 0.19	<0.001
HbA1c (%)	6.23 ± 0.03	5.98 ± 0.05	<0.001
Hypertension (%)	70.81	63.75	0.02
SBP (mmHg)	129.47 ± 0.36	126.92 ± 0.72	0.003
DBP (mmHg)	77.59 ± 0.23	76.97 ± 0.46	0.25
Total cholesterol (mmol/L)	3.91 ± 0.03	4.01 ± 0.05	0.09
Triglyceride (mmol/L)	1.79 ± 0.04	1.72 ± 0.07	0.40
LDL-C (mmol/L)	2.00 ± 0.02	2.08 ± 0.05	0.12
HDL-C (mmol/L)	1.14 ± 0.01	1.22 ± 0.02	<0.001
Smoking states			<0.001
Nonsmokers (%)	47.41	62.14
Ex-smokers (%)	8.54	5.18
Current smokers (%)	44.05	32.69
Statin use (%)	53.76	35.60	<0.001
Free T4 (pmol/L)	15.28 ± 0.06	15.76 ± 0.22	0.11
TSH (uIU/mL)	2.59 ± 0.09	2.38 ± 0.17	0.30
Thyroid function state (%)			0.52
Hyperthyroidism	0.67	0.97
Euthyroidism	87.92	90.29
Subclinical hypothyroidism	9.60	7.12
Overt hypothyroidism	1.81	1.62

Comparison between coronary heart disease and noncoronary heart disease.
FPG: fasting plasma glucose; 2-h PPG: 2-hour postprandial plasma glucose; HbA1c: glycosylated hemoglobin; SBP: systolic blood pressure; DBP: diastolic blood pressure; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; TSH: thyroid stimulating hormone.