Research Article

Are Thyroid Hormone and Tumor Cell Proliferation in Human Breast Cancers Positive for HER2 Associated?

Table 1

Comparison of thyroid hormone levels in breast cancer patients based on menopausal status, clinical stage, histopathological grade, and HER2 staining.

MenopauseSignificance
NoYes

FT32.97 (0.12)2.92 (0.05) = 0.66
FT41.39 (0.05)1.36 (0.03) = 0.60
TSH1.67 (0.19)1.58 (0.13) = 0.70

Clinical stage
IIIIIIIV

FT32.88 (0.15)2.95 (0.05)2.95 (0.13)2.97 (0.13) = 0.94
FT41.36 (0.06)1.38 (0.04)1.36 (0.07)1.32 (0.08) = 0.90
TSH1.35 (0.19)1.58 (0.14)2.04 (0.32)1.85 (0.6) = 0.27

Histopathological grade
Grade 1Grade 2Grade 3

FT32.77 (0.18)2.95 (0.06)2.97 (0.14) = 0.59
FT41.26 (0.08)1.36 (0.03)1.45 (0.07) = 0.26
TSH2.18 (0.67)1.64 (0.11)1.21 (0.3) = 0.16

HER2 staining
NegativePositive

FT33.0 (0.07)2.9 (0.06) = 0.35
FT41.36 (0.06)1.37 (0.03) = 0.88
TSH1.74 (0.25)1.57 (0.12) = 0.50