International Journal of Endocrinology

Research Article

Predictors of Subclinical Cardiovascular Disease in Women with Polycystic Ovary Syndrome: Interrelationship of Dyslipidemia and Arterial Blood Pressure

Table 2

Clinical and biochemical parameters in women with PCOS and controls related to age.


Parameter	Age <30 years ()			Age ≥30 years ()			PCOS <30 years versus PCOS ≥30 years		Controls <30 years versus controls ≥30 years value
Parameter	PCOS ()	Controls ()	value	PCOS ()	Controls ()	value	value	value adjusted for BMI	Controls <30 years versus controls ≥30 years value

BMI (kg/m²)	23.32 ± 4.94	24.10 ± 6.65	0.507	30.2 ± 7.6	25.69 ± 6.86	0.059	<0.001	/	0.437
WHR	0.82 ± 0.11	0.79 ± 0.07	0.209	0.89 ± 0.09	0.81 ± 0.07	0.006	0.008	0.558	0.442
SBP (mmHg)	116.97 ± 9.14	117.66 ± 11.84	0.744	127.68 ± 13.62	117.5 ± 12.16	0.016	<0.001	0.003	0.965
DBP (mmHg)	75.28 ± 8.17	75.31 ± 9.67	0.986	84.11 ± 10.31	76.94 ± 8.93	0.023	<0.001	0.003	0.559
TC (mmol/L)	4.94 ± 9.60	4.84 ± 0.89	0.597	5.46 ± 1.07	5.23 ± 1.24	0.523	0.028	0.235	0.204
HDL-C (mmol/L)	1.40 ± 0.34	1.36 ± 0.26	0.493	1.23 ± 0.27	1.4 ± 0.32	0.076	0.028	0.669	0.608
LDL-C (mmol/L)	3.07 ± 0.82	2.97 ± 0.69	0.555	3.49 ± 0.99	3.39 ± 1.23	0.770	0.045	0.294	0.128
TG (mmol/L)	1.04 ± 0.52	1.13 ± 0.82	0.604	1.71 ± 1.06	0.98 ± 0.45	0.009	<0.001	0.050	0.483
Glucose (mmol/L)	4.64 ± 0.47	4.62 ± 0.37	0.793	4.87 ± 0.61	4.61 ± 0.51	0.145	0.056	0.337	0.936
Insulin (mU/L)	15.83 ± 8.87	14.73 ± 7.55	0.545	17.96 ± 11.71	19.08 ± 11.16	0.765	0.348	0.028	0.117
HOMA	3.30 ± 1.99	3.0 ± 1.49	0.451	3.96 ± 3.02	3.89 ± 2.37	0.942	0.331	0.080	0.183
Apo-A1 (g/L)	1.61 ± 0.33	1.68 ± 0.36	0.329	1.51 ± 0.25	1.54 ± 0.22	0.706	0.202	0.790	0.145
Apo-B (g/L)	0.87 ± 0.29	0.82 ± 0.22	0.383	1.04 ± 0.27	0.95 ± 0.31	0.354	0.014	0.490	0.074
TC/HDL-C	3.69 ± 1.10	3.68 ± 0.99	0.947	4.57 ± 1.09	3.96 ± 1.54	0.140	0.001	0.329	0.435
TG/HDL-C	0.84 ± 0.59	0.93 ± 0.86	0.520	1.51 ± 1.10	0.77 ± 0.49	0.012	<0.001	0.137	0.470
Testosterone (nmol/L)	2.56 ± 0.95	1.70 ± 0.60	<0.001	2.99 ± 1.05	1.53 ± 0.61	<0.001	0.061	0.158	0.348
SHBG (nmol/L)	39.19 ± 20.94	53.18 ± 27.19	0.012	37.03 ± 29.63	60.06 ± 39.65	0.037	0.693	0.167	0.472
FAI	9.76 ± 10.95	4.20 ± 2.68	<0.001	11.39 ± 7.55	3.92 ± 3.07	<0.001	0.499	0.043	0.735
Androstenedione (ng/mL)	3.38 ± 1.27	2.27 ± 1.18	<0.001	3.44 ± 1.67	1.9 ± 0.95	0.03	0.862	0.964	0.302
DHEAS (nmol/L)	8.46 ± 4.18	6.03 ± 3.08	0.004	7.16 ± 3.29	4.12 ± 2.20	0.002	0.175	0.082	0.025

BMI: body mass index; WHR, waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; TG: triglycerides; HOMA: homeostatic model assessment; Apo-A1: apolipoprotein A1; Apo-B: apolipoprotein B; DHEAS: dehydroepiandrosterone sulfate; SHBG: sex-hormone-binding globulin; FAI: free androgen index.