Research Article

Evidence of Insulin Resistance and Other Metabolic Alterations in Boys with Duchenne or Becker Muscular Dystrophy

Table 1

Anthropometric and metabolic parameters in the study sample of DMD/BMD patients ( = 66).

Median Minimum, maximum

Age (years) 8.96 4.61, 17.75
Body weight (kg)25.812.40, 79.35
Height (mts) 1.23 0.97, 1.75
BMI (kg/m2)16.0510.40, 29.50
Percentile47.5 0.0, 99.74
Body fat (%)26.2 7.62, 60.0
Body fat mass (kg) 6.370.88, 46.08
Fat-free mass (kg) 
Glucose (mg/dL)
16.89 
91.8
10.69, 34.99 
72, 135
Insulin (U/mL)  
>12 (U/mL)
11.75  
48.5%
5.2, 59.9
HOMA-IR 
IR > 3.16
2.6  
36.4%
1.04, 12.91
Loss of ambulation18

DMD/BMD: Duchene/Becker muscular dystrophy; BMI: body mass index; IR: insulin resistance; HOMA-IR: homeostasis model assessment-insulin resistance.