Research Article

Sexual Dimorphisms of Adrenal Steroids, Sex Hormones, and Immunological Biomarkers and Possible Risk Factors for Developing Rheumatoid Arthritis

Table 2

Logistic regression model of sex outcome, including age and serum inflammatory biomarkers, but not IL-6 assayed only in females.

Variables in the modelTotal ()Controls ()
Wald values Wald values

C-reactive protein (CRP)1.5650.2110.8440.358
Acute serum amyloid A (ASAA)11.1630.0019.160.002
Interleukin-1β (IL-1β)0.0920.7620.5180.472
Interleukin-1 receptor antagonist0.9450.3311.5620.211
Tumor necrosis factor-α (TNF-α)0.1820.6691.4370.231
Soluble interleukin-2Rα (sIL-2Rα)4.0320.0453.8130.051
Soluble tumor necrosis receptor 1 14.409<0.00110.7210.001
Age at entry4.0370.0451.9240.165
Constant10.7240.0018.2570.004

1 df for each variable entered in block.