Sexual Dimorphisms of Adrenal Steroids, Sex Hormones, and Immunological Biomarkers and Possible Risk Factors for Developing Rheumatoid Arthritis

Table 8

(a) Control subjects () pattern matrix. (b) Pre-RA subjects () pattern matrix.

(a)

Variables in model (variance extracted = 72.7%)	Principal components extracted
		2	3	4
	(AA steroids)	(Receptors)	(IL-1β/ra)	(Cortisol)
Age at entry	−.556	.198	.250	.190
dhea_silW_new	.870	−.006	−.010	.209
adione_slW_new	.871	.048	−.050	.225
test_silW_new	.767	.079	.162	−.137
il_2_alplW_new	−.026	.822	.073	.107
stnf_r1lW_new	.042	.865	−.157	−.118
il_1_betlW_new	−.109	−.060	−.881	.185
il_1ralW_new	.131	.183	−.722	−.201
cort_silW_new	.115	.003	−.043	.934

Rotation method: Oblimin with Kaiser normalization, in 5 iterations.
Androgenic anabolic (AA) steroids are first extracted and inverse with age.

(b)

Variables in model (variance extracted = 62.3%)	Principal components extracted
		2	3
	(AA steroids)	(Receptors)	(Cortisol)
Age at entry	−0.596	−0.266	0.128
dhea_silW_new	0.809	−0.250	0.188
adione_slW_new	0.851	−0.137	0.020
test_silW_new	0.623	0.025	−0.380
il_2_alplW_new	−0.108	0.816	−0.043
stnf_r1lW_new	0.082	0.822	0.279
il_1_betlW_new	0.688	0.209	−0.065
il_1ralW_new	0.006	0.205	0.905
cort_silW_new	0.504	−0.150	0.213

Rotation method: Oblimin with Kaiser normalization, in 6 iterations.
IL-1β and cortisol are first extracted with the AA steroids.