Research Article

Differential Regulation of Morphology and Estrogen Receptor-Alpha Expression in the Vagina of Ovariectomized Adult Virgin Rats by Estrogen Replacement: A Histological Study

Figure 1

H&E immunostaining of vaginal tissue sections. (a)–(f) show H&E immunostaining of vaginal tissue sections from sham, OVX, E1, E2, E3, and E4 groups, respectively. The atrophic vaginal squamous epithelium in the OVX group is indicated by a red arrow in (b), exhibiting reduced epithelial stratification and cornification. Scale bar represents 50 μm (200x magnification). H&E, hematoxylin & eosin.
(a)
(b)
(c)
(d)
(e)
(f)